ACVR2A Recombinant Rabbit Monoclonal Antibody (ARC1220), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535684-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA535684 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
ACVR2A
Classification
Monoclonal
Concentration
1.5 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P27037, P27038, P38444
Gene Symbols
ACVR2A
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ACVR2A (P27037)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
ARC1220
Conjugate
Unconjugated
Gene
ACVR2A
Gene Alias
activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11480, 29263, 92
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Immunogen sequence: MGAAAKLAFA VFLISCSSGA ILGRSETQEC LFFNANWEKD RTNQTGVEPC YGDKDKRRHC FATWKNISGS IEIVKQGCWL DDINCYDRTD CVEKKDSPEV Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases
- ACVR2A is involved in the activin and myostatin signaling pathway
- (ACVR2A Aliases: ACVR2, ACTRII)
- These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity
- Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors
- Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
- Type II receptors are considered to be constitutively active kinases.