PIMA535940

SARS-CoV-2 Spike Protein S1 Chimeric Recombinant Human Monoclonal Antibody (H6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA535940-Each-of-1 In Stock ₹ 87,175.50

PIMA535940 - Each of 1

₹ 87,175.50

In Stock

Quantity

1

Base Price: ₹ 87,175.50

GST (18%): ₹ 15,691.59

Total Price: ₹ 1,02,867.09

Antigen

SARS-CoV-2 Spike Protein S1 Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Host Species

Human

Purification Method

Affinity chromatography

Regulatory Status

RUO

Target Species

Virus

Product Type

Antibody

Isotype

IgG1 κ

Applications

ELISA, Lateral Flow

Clone

H6

Conjugate

Unconjugated

Gene Alias

Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2

Immunogen

Recombinant Human Novel Coronavirus Spike glycoprotein (S) (16-685aa)

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • Recombinant anti-SARS-CoV-2 spike is expressed from 293 cells (HEK293)
  • It is a chimeric monoclonal antibody combining the mouse variable regions with the constant domains of human IgG1
  • SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress
  • SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain (Spike Protein)
  • The Spike protein is the main surface antigen of the coronavirus
  • The glycosylated Spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients
  • S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells
  • CoV diversity is reflected in the variable Spike proteins (S proteins), which have evolved into forms differing in their receptor interactions and their response to various environmental triggers of virus-cell membrane fusion.