PSMD14 Recombinant Rabbit Monoclonal Antibody (JE48-88), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA536140-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA536140 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
PSMD14
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O00487, O35593
Gene Symbols
PSMD14
Immunogen
Recombinant protein within Human PSMD14 aa 92-230
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
JE48-88
Conjugate
Unconjugated
Gene
PSMD14
Gene Alias
2610312C03Rik; 26S proteasome non-ATPase regulatory subunit 14; 26S proteasome non-ATPase subunit; 26S proteasome regulatory subunit rpn11; 26S proteasome-associated pad1 homolog; 26S proteasome-associated PAD1 homolog 1; 3200001M20Rik; AA986732; MAD1; PAD1; POH1; proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; proteasome 26S subunit, non-ATPase 14; Psmd14; rpm11; RPN11; testis tissue sperm-binding protein Li 69n
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10213, 311078, 59029
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- The 26S proteasome is responsible for most intracellular proteolysis in eukaryotes
- POH1 (also known as Rpn11 in yeast) subunit of the 19S complex is responsible for substrate deubiquitination during proteasomal degradation
- POH1 appears to be a Zn21-dependent protease, unlike all other known deubiquitinating enzymes (DUBs) that are cysteine proteases
- POH1 was first identified as the human functional homolog of the S
- pombe pad1 gene, which confers moderate resistance to chemotherapeutic drugs, and also to μgtraviolet light when transiently overproduced in mammalian cells
- Poh1-induced drug resistance is mediated through AP-1 transcription factors.