PIMA536256

Ras (G12D Mutant) Recombinant Rabbit Monoclonal Antibody (HL10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA536256-Each-of-1 In Stock ₹ 50,418.50

PIMA536256 - Each of 1

₹ 50,418.50

In Stock

Quantity

1

Base Price: ₹ 50,418.50

GST (18%): ₹ 9,075.33

Total Price: ₹ 59,493.83

Antigen

Ras (G12D Mutant)

Classification

Monoclonal

Concentration

1.5 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P01111, P08556

Gene Symbols

NRAS

Immunogen

Synthetic peptide corresponding to human RAS (G12D Mutant).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

HL10

Conjugate

Unconjugated

Gene

NRAS

Gene Alias

ALPS4; AV095280; CMNS; GTPase NRas; HRAS1; NCMS; neuroblastoma ras oncogene; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; NRAS; N-ras; N-ras protein part 4; NRAS1; NS6; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18176, 4893

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Ras is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane
  • The process of shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex
  • The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein
  • Mutations in Ras gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.