PIMA536980

Phospho-Shp2 (Tyr580) Recombinant Rabbit Monoclonal Antibody (Shp2Y580-4A2), APC, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA536980-Each-of-1 In Stock ₹ 50,151.50

PIMA536980 - Each of 1

₹ 50,151.50

In Stock

Quantity

1

Base Price: ₹ 50,151.50

GST (18%): ₹ 9,027.27

Total Price: ₹ 59,178.77

Antigen

Phospho-Shp2 (Tyr580)

Classification

Monoclonal

Conjugate

APC

Gene

PTPN11

Gene Alias

2700084A17Rik; AW536184; bptp3; CFC; cSH-PTP2; encodes catalytic domain; HCP; HGNC:9644; JMML; METCDS; MGC14433; Noonan syndrome 1; ns1; null; OTTHUMP00000166108; phosphotyrosyl-protein phosphatase; protein tyrosine phosphatase non-receptor type 11; protein tyrosine phosphatase SH-PTP2; protein tyrosine phosphatase, non-receptor type 11; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); protein tyrosine phosphatase, non-receptor type 11 S homeolog; protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; protein-tyrosine phosphatase SYP; PTP1C; PTP1D; PTP-1D; ptp-2; PTP2C; PTP-2C; Ptpn11; ptpn11.S; ptpn11-a; ptpn11-b; SAP-2; SH2 domain-containing protein tyrosine phosphatase-2; Shp2; shp-2; SHPTP2; SH-PTP2; SH-PTP2 protein tyrosine phosphatase non-receptor type 11; SH-PTP2 protein tyrosine phosphatase, non-receptor type 11; SH-PTP3; Syp; Tyrosine-protein phosphatase non-receptor type 11; XELAEV_18010676mg

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

19247, 5781

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry

Clone

Shp2Y580-4A2

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.

P35235, Q06124

Gene Symbols

PTPN11

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr580 of human phospho Shp2.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG κ

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Description

  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family
  • PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
  • This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates
  • This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration
  • Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.