Phospho-Btk (Tyr551) Recombinant Rabbit Monoclonal Antibody (BtkY551-G12), PE, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537367-Each-of-1 | In Stock | ₹ 19,758.00 |
PIMA537367 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 19,758.00
GST (18%): ₹ 3,556.44
Total Price: ₹ 23,314.44
Antigen
Phospho-Btk (Tyr551)
Classification
Monoclonal
Conjugate
PE
Gene
BTK
Gene Alias
agammaglobulinaemia tyrosine kinase; agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton's tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD1; Kinase EMB; MGC126261; MGC126262; OTTHUMP00000023677; PSCTK1; RP1-164F3.2; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking exon 14); xid; XLA; X-linked immune deficiency
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
695
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
BtkY551-G12
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.
Q06187
Gene Symbols
BTK
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr551 of human phospho Btk.
Quantity
10 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG κ
Related Products
Description
- Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases
- Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders
- It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9
- The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens
- BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction.