PIMA537611

IGHA1 Monoclonal Antibody (585CT26.3.1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA537611-Each-of-1 In Stock ₹ 47,481.50

PIMA537611 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

IGHA1

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.09% sodium azide

Gene Accession No.

P01876

Gene Symbols

IGHA1

Immunogen

KLH conjugated synthetic peptide between 150-178 amino acids from the Central region of human lgA

Regulatory Status

RUO

Gene ID (Entrez)

3493

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Clone

585CT26.3.1

Conjugate

Unconjugated

Gene

IGHA1

Gene Alias

IgA1; IGHA1; IGHA2; immunoglobulin heavy constant alpha 1; immunoglobulin heavy constant alpha 2 (A2m marker)

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgM

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Description

  • Constant region of immunoglobulin heavy chains
  • Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes
  • In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells
  • Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268)
  • The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain
  • Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen
  • The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)
  • Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915)
  • [UniProt]