PIMA538310

GATA3 Recombinant Rabbit Monoclonal Antibody (2A9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538310-Each-of-1 In Stock ₹ 53,088.50

PIMA538310 - Each of 1

₹ 53,088.50

In Stock

Quantity

1

Base Price: ₹ 53,088.50

GST (18%): ₹ 9,555.93

Total Price: ₹ 62,644.43

Antigen

GATA3

Classification

Recombinant Monoclonal

Concentration

1.2 mg/mL

Formulation

PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P23771

Gene Symbols

GATA3

Immunogen

A synthesized peptide derived from human GATA3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

2A9

Conjugate

Unconjugated

Gene

GATA3

Gene Alias

EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2625

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • This antibody has been tested in direct-ELISA The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins
  • Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes
  • GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain
  • GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages
  • GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers
  • Labastie et al
  • (1994) cloned the human gene and the 5-prime end of the mouse gene
  • The human gene comprises 6 exons distributed over 17 kb of DNA
  • Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.