PIMA538392

COX1 Recombinant Rabbit Monoclonal Antibody (6B6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538392-Each-of-1 In Stock ₹ 53,088.50

PIMA538392 - Each of 1

₹ 53,088.50

In Stock

Quantity

1

Base Price: ₹ 53,088.50

GST (18%): ₹ 9,555.93

Total Price: ₹ 62,644.43

Antigen

COX1

Classification

Recombinant Monoclonal

Concentration

0.33 mg/mL

Formulation

PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P22437, P23219

Gene Symbols

COX1, PTGS1

Immunogen

A synthesized peptide derived from human COX1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Western Blot

Clone

6B6

Conjugate

Unconjugated

Gene

PTGS1

Gene Alias

COI; COX1; Cox-1; COX3; Cox-3; COXI; cyclooxygenase 3; cyclooxygenase precursor (EC 1.14.99.1); cyclooxygenase-1; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; Mtco1; mt-Co1; P PGG/HS; PCOX1; PES-1; PGG/HS; PGH synthase 1; PGHS1; Pghs-1; PHS 1; PHS1; prostaglandin endoperoxide synthase; prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase; prostaglandin G/H synthase precursor (EC 1.14.99.1); prostaglandin H2 synthase 1; Prostaglandin-endoperoxide synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); PTGHS; PTGS1; unnamed protein product

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19224, 4512, 5742

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • This antibody has been tested in direct-ELISA PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase
  • There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution
  • This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin
  • PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis
  • Alternative splicing of this gene generates two transcript variants
  • The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.