PIMA538439

ADAM10 Monoclonal Antibody (6C3C7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538439-Each-of-1 In Stock ₹ 48,371.50

PIMA538439 - Each of 1

₹ 48,371.50

In Stock

Quantity

1

Base Price: ₹ 48,371.50

GST (18%): ₹ 8,706.87

Total Price: ₹ 57,078.37

Antigen

ADAM10

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O14672

Gene Symbols

Adam10

Immunogen

Purified recombinant fragment of human ADAM10 (aa: EXTRA(20-119)) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

6C3C7

Conjugate

Unconjugated

Gene

Adam10

Gene Alias

1700031C13Rik; a disintegrin and metallopeptidase domain 10; a disintegrin and metalloprotease domain (ADAM) 10; a disintegrin and metalloprotease domain 10; a disintegrin and metalloproteinase; AD10; AD18; ADAM; ADAM 10; ADAM metallopeptidase domain 10; ADAM10; ADAMs; CD156c; CDw156; Disintegrin and metalloproteinase domain-containing protein 10; HsT18717; KUZ; kuzbanian; kuzbanian protein homolog; MADM; Mammalian disintegrin-metalloprotease; metalloendopeptidases; metalloproteinase; myelin-associated metalloproteinase; RAK

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

102

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody has been tested in indirect ELISA
  • Proinflammatory cytokine tumor necrosis factor-a (TNF-a) contributes to a variety of inflammatory responses and programmed cell death
  • Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma
  • TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor
  • ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3)
  • The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively
  • ADAM10 mRNA is expressed in a variety of human and bovine tissues.