MECP2 Monoclonal Antibody (8H4A5B9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA538570-Each-of-1 | In Stock | ₹ 48,371.50 |
PIMA538570 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,371.50
GST (18%): ₹ 8,706.87
Total Price: ₹ 57,078.37
Antigen
MECP2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P51608
Gene Symbols
Mecp2
Immunogen
Purified recombinant fragment of human MECP2 (aa: 7-148) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
8H4A5B9
Conjugate
Unconjugated
Gene
Mecp2
Gene Alias
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
4204
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody has been tested in indirect ELISA
- MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain
- MECP2 is capable of binding specifically to methylated DNA
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
- MECP2 can also repress transcription from methylated gene promoters
- In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation
- MECP2 is dispensible in stem cells, but is essential for embryonic development
- MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.