CD31 (PECAM-1) Recombinant Rabbit Monoclonal Antibody (008), APC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA541008-Each-of-1 | In Stock | ₹ 44,455.50 |
PIMA541008 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,455.50
GST (18%): ₹ 8,001.99
Total Price: ₹ 52,457.49
Antigen
CD31 (PECAM-1)
Classification
Recombinant Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 0.5% BSA and 0.09% sodium azide
Gene Accession No.
Q08481
Gene Symbols
Pecam1
Immunogen
Recombinant Mouse CD31/PECAM-1 Protein
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Mouse
Form
Liquid
Applications
Flow Cytometry
Clone
008
Conjugate
APC
Gene
Pecam1
Gene Alias
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18613
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Isotype
IgG
Related Products
Description
- May be stored for twelve months without detectable loss of activity
- Protect from prolonged exposure to light and do not freeze
- Sodium azide is toxic to cells and should be disposed of properly so flush with large volumes of water during disposal
- CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases
- CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells
- N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions
- CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis
- It is one of key regulatory molecules in vascular system.