PIMA542421

RNF20 Recombinant Rabbit Monoclonal Antibody (SP00-47), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA542421-Each-of-1 In Stock ₹ 45,790.50

PIMA542421 - Each of 1

₹ 45,790.50

In Stock

Quantity

1

Base Price: ₹ 45,790.50

GST (18%): ₹ 8,242.29

Total Price: ₹ 54,032.79

Antigen

RNF20

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q5DTM8, Q5VTR2

Gene Symbols

RNF20

Immunogen

Recombinant protein within human rnf20 aa 480-585

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

SP00-47

Conjugate

Unconjugated

Gene

RNF20

Gene Alias

4833430L21Rik; AW540162; BRE1; BRE1 E3 ubiquitin ligase homolog; BRE1A; BRE1-A; C79397; E3 ubiquitin-protein ligase BRE1A; FLJ11189; FLJ20382; hBRE1; HNF3B; homolog of S. cerevisiae BRE1; hypothetical protein; KIAA2779; Kiaa4116; MGC129667; MGC129668; mKIAA4116; RCJMB04_5a23; RING finger protein 20; ring finger protein 20, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1A; Rnf20; TCF3B

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

109331, 56254

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Positive Control: Jurkat, MCF-7, Hela
  • Subcellular Location: Nucleus
  • RNF20 is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B
  • RNF20 selectively suppresses the expression of some genes such as several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS)
  • In contrast, RNF20 also positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes
  • Together with the deubiquitinase USP44, RNF20 regulates stem cell differentiation by modulating H2B monoubiquitination.