PIMA542774
Zyxin Recombinant Rabbit Monoclonal Antibody (4F9P3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542774-Each-of-1 | In Stock | ₹ 45,790.50 |
PIMA542774 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,790.50
GST (18%): ₹ 8,242.29
Total Price: ₹ 54,032.79
Antigen
Zyxin
Classification
Recombinant Monoclonal
Concentration
1.1 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q15942, Q62523
Gene Symbols
ZYX
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Zyxin (Q15942).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
4F9P3
Conjugate
Unconjugated
Gene
ZYX
Gene Alias
9530098H06Rik; ESP-2; HED-2; LOW QUALITY PROTEIN: zyxin; R75157; ZYX; Zyxin; zyxin-2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22793, 7791
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Positive test controls include: MCF7, Mouse lung
- The target is usually found in the following locations: Cell junction, Cytoplasm, Nucleus, cytoskeleton, focal adhesion
- Immunogen sequence: TQPRGPPASS PAPAPKFSPV TPKFTPVASK FSPGAPGGSG SQPNQKLGHP EALSAGTGSP QPPSFTYAQQ REKPRVQEKQ HPVPPPAQNQ NQVRSPGAPG P Zyxin is involved in focal adhesions, which are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble
- Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton
- Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half
- The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding
- Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles
- Alternative splicing results in multiple transcript variants that encode the same isoform.