Caveolin 3 Recombinant Rabbit Monoclonal Antibody (4G5W2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542865-Each-of-1 | In Stock | ₹ 45,790.50 |
PIMA542865 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,790.50
GST (18%): ₹ 8,242.29
Total Price: ₹ 54,032.79
Antigen
Caveolin 3
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P51637, P51638, P56539
Gene Symbols
Cav3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-151 of human Caveolin-3 (P56539)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
4G5W2
Conjugate
Unconjugated
Gene
Cav3
Gene Alias
AI385751; CAV; Cav3; Cav-3; caveolin 3; caveolin-3; LGMD1C; LQT9; M-cav; M-caveolin; MGC126100; MGC126101; MGC126129; structural protein; VIP21; VIP-21
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12391, 29161, 859
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Positive test controls include: Mouse lung, Mouse heart, Rat heart
- The target is usually found in the following locations: Cell membrane, Golgi apparatus membrane, Membrane, Peripheral membrane protein, caveola
- Immunogen sequence: MMAEEHTDLE AQIVKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPVG TYSFDGVWKV SYTTFTVSKY WCYRLLSTLL GVPLALLWGF LFACISFCHI WAVVPCIKSY LIEIQCISHI YSLCIRTFCN PLFAALGQVC SSIKVVLRKE V Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane
- It interacts directly with G-protein alpha subunits and can functionally regulate their activity
- Caveolin-3 may also regulate voltage-gated potassium channels
- It also plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress
- Caveolin-3 also mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae
- Mutations in the gene can result in HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.