PIMA543845
Thioredoxin 1 Monoclonal Antibody (3#), Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA543845-Each-of-1 | In Stock | ₹ 17,702.10 |
PIMA543845 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,702.10
GST (18%): ₹ 3,186.378
Total Price: ₹ 20,888.478
Antigen
Thioredoxin 1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
P10599
Gene Symbols
TXN
Immunogen
Met1-Val105 (Accession P10599), with N-terminal His Tag
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Applications
Western Blot
Clone
3#
Conjugate
Unconjugated
Gene
TXN
Gene Alias
ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
7295
Content And Storage
-20°C
Form
Liquid
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Description
- Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells
- Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site
- The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds
- Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor
- The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations
- Specific protein disulfide targets for reduction by Trx include protein disulfide-isomerase (PDI) and a number of transcription factors such as p53, NF-kB and AP-1 (T1-151)
- Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.