PIMA544555
B-Raf (V600E) Recombinant Rabbit Monoclonal Antibody (RM8), Biotin, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544555-Each-of-1 | In Stock | ₹ 39,961.00 |
PIMA544555 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,961.00
GST (18%): ₹ 7,192.98
Total Price: ₹ 47,153.98
Antigen
B-Raf (V600E)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P15056
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
673
Content And Storage
-20°C
Isotype
IgG
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
RM8
Conjugate
Biotin
Gene
BRAF
Gene Symbols
BRAF
Immunogen
A peptide corresponding to BRAF V600E mutant. The immunogen range is a synthetic peptide within amino acids 550-650 of Akt with V600E mutant.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- This antibody reacts to the Histone H3.3 G34R mutant
- No cross reactivity with wild type Histone H3.3
- This gene, B-RAF/BRAF, encodes a protein belonging to the RAF family of serine/threonine protein kinases
- This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion
- Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung
- Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes
- A pseudogene of this gene has been identified on the X chromosome.