PIMA545309

TRAP1 Monoclonal Antibody (3H4-2H6), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545309-Each-of-1 In Stock ₹ 38,181.00

PIMA545309 - Each of 1

₹ 38,181.00

In Stock

Quantity

1

Base Price: ₹ 38,181.00

GST (18%): ₹ 6,872.58

Total Price: ₹ 45,053.58

Antigen

TRAP1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.

Q12931, Q5XHZ0, Q9CQN1

Gene Symbols

Trap1

Immunogen

Purified recombinant TRAP1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

3H4-2H6

Conjugate

FITC

Gene

Trap1

Gene Alias

2410002K23Rik; heat shock protein 75 kDa, mitochondrial; HSP 75; HSP75; HSP90L; testicular tissue protein Li 209; TNF receptor associated protein 1; TNF receptor-associated protein 1; TNFR-associated protein 1; TRAP1; TRAP-1; tumor necrosis factor type 1 receptor associated protein; tumor necrosis factor type 1 receptor-associated protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

10131, 287069, 68015

Content And Storage

4° C, store in dark

Isotype

IgG1 κ

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Description

  • 1 μg/mL of MA5-45309 was sufficient for detection of Trap-1/HSP75 in 20 μg of Human A431 lysate by ECL immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.∣Detects approximately 75kDa
  • The 90 kDa heat shock protein (hsp90) family of molecular chaperones is a highly conserved family of proteins that play an important physiological role
  • Hsp90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery
  • A recently cloned homolog of hsp90 is the tumor necrosis factor receptor-associated protein (TRAP1)
  • Like hsp90, TRAP1 is found to be associated with numerous proteins involved in diverse actions
  • Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells
  • This observation and the fact that TRAP1 is shown to have a mitochondrial targeting presequence strongly implicates TRAP1 as a mitochondrial matrix protein.