PIMA545540

Ankyrin G Monoclonal Antibody (S106-20), APC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545540-Each-of-1 In Stock ₹ 40,317.00

PIMA545540 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

Ankyrin G

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.

G5E8K5, O70511, Q12955

Gene Symbols

ANK3

Immunogen

Fusion protein 1000 C-terminal amino acids of human Ankyrin G (also known as ANK-3 or ankyrin-3) encompassing all of Ankyrin G with the exception of Ankyrin repeats

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

S106-20

Conjugate

APC

Gene

ANK3

Gene Alias

2900054D09Rik; AI314020; ANK3; ANK-3; AnkG; ankyrin 3; ankyrin 3 (G); ankyrin 3, epithelial; ankyrin 3, node of Ranvier (ankyrin G); ankyrin G; ankyrin-3; Ankyrin-G; brain-specific ankyrin-G; LOW QUALITY PROTEIN: ankyrin-3; MRT37

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

11735, 288, 361833

Content And Storage

4° C

Isotype

IgG1

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Description

  • 1 μg/mL of MA5-45540 was sufficient for detection of Ankyrin-G in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.∣Detects >approximately 200kDa
  • Ankyrin-G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier
  • Ankyrin-G is also found at sites of epithelial cell-cell contact and in the intracellular membranes of some cells
  • Ankyrin-G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain
  • Ankyrin-G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.