PIMA545545

CaV3.1 Monoclonal Antibody (S178A-9), PerCP, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545545-Each-of-1 In Stock ₹ 40,317.00

PIMA545545 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

CaV3.1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.

O43497, O54898

Gene Symbols

CACNA1G

Immunogen

Fusion protein amino acids 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

S178A-9

Conjugate

PerCP

Gene

CACNA1G

Gene Alias

[a]1G; a1G; alpha-1G; Ca(V)T.1; CACNA1G; calcium channel, voltage-dependent, T type, alpha 1G subunit; calcium voltage-gated channel subunit alpha1 G; CaV T1; Cav3 1; cav3 1c; Cav3.1; Cav3.1c; Cav3.1d; KIAA1123; MGC117234; mKIAA1123; NBR13; SCA42; voltage-dependent calcium channel alpha 1G subunit, isoform 11; voltage-dependent T-type calcium channel alpha 1G subunit; voltage-dependent T-type calcium channel subunit alpha-1G; Voltage-gated calcium channel subunit alpha Cav3.1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12291, 29717, 8913

Content And Storage

4° C

Isotype

IgG1

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Description

  • 1 μg/mL of MA5-45545 was sufficient for detection of Cav3.1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately <200kDa
  • Does not cross-react with Cav3.2
  • Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca2+-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression
  • Calcium channels are highly diverse, multimeric complexes composed of an alpha-1 subunit, an intracellular beta subunit, a disulfide linked alpha-2/delta subunit and a transmembrane gamma subunit
  • Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types
  • T-type Ca2+ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca2+ current types
  • T-type Ca2+ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).