GAD65 Monoclonal Antibody (144), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA546586-Each-of-1 | In Stock | ₹ 32,663.00 |
PIMA546586 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,663.00
GST (18%): ₹ 5,879.34
Total Price: ₹ 38,542.34
Antigen
GAD65
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P48320, Q05329, Q05683
Gene Symbols
GAD2
Immunogen
Synthetic peptide: GSGFWSFGSEDGSGDSEN conjugated to KLH, corresponding to amino acids 4-22 of Human GAD65
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Flow Cytometry
Clone
144
Conjugate
PE
Gene
GAD2
Gene Alias
6330404F12Rik; 65 kDa glutamic acid decarboxylase; GAD(65); GAD2; Gad-2; GAD65; GAD-65; Glutamate decarboxylase 2; Glutamate decarboxylase 2 (islet); glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase-2 (pancreas); glutamic acid decarboxylase 2; glutamic acid decarboxylase 65; MGC161605; MGC161607; RP11-420F12.2
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14417, 24380, 2572
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- GAD65 (glutamic acid decarboxylase-65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease
- Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity
- These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67
- Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD.