PIMA547156

SARS-CoV-2 ORF3a Recombinant Rabbit Monoclonal Antibody (HL1722), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547156-Each-of-1 In Stock ₹ 40,317.00

PIMA547156 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

SARS-CoV-2 ORF3a

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Target Species

Virus

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

HL1722

Conjugate

Unconjugated

Gene Alias

COVID19 ORF3A; COVID-19 ORF3A; ORF3A; SARS-CoV-2 Open Reading Frame 3A; SARS-COV2 ORF3A

Immunogen

Recombinant protein encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) ORF3a. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • ORF3A forms homotetrameric potassium sensitive ion channels (viroporin) and may modulate virus release
  • Up-regulates expression of fibrinogen subunits FGA, FGB and FGG in host lung epithelial cells
  • Induces apoptosis in cell culture
  • Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.