beta Synuclein Monoclonal Antibody (6A10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547356-Each-of-1 | In Stock | ₹ 1,49,520.00 |
PIMA547356 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,49,520.00
GST (18%): ₹ 26,913.60
Total Price: ₹ 1,76,433.60
Antigen
beta Synuclein
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.
P33567, Q16143, Q63754, Q91ZZ3
Gene Symbols
SNCB
Immunogen
C-terminal peptide of human beta-synuclein EPEGESYEDPPQEEYQEYEPEA coupled to KLH
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
Clone
6A10
Conjugate
Unconjugated
Gene
SNCB
Gene Alias
AI838531; betaSYN; beta-synuclein; Phosphoneuroprotein 14; PNP 14; Sncb; synuclein beta; synuclein, beta
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
100127169, 104069, 113893, 508421, 6620
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals
- In vertebrates they are encoded by three different genes
- Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer
- In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid
- In PD, an alpha synuclein accumulates in Lewy bodies
- An allele of alpha synuclein has been linked to many familial cases of PD
- In breast cancer increased expression of gamma synuclein correlates with the disease progression
- Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.