PIMA547672

CD298 Monoclonal Antibody (M016), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547672-Each-of-1 In Stock ₹ 47,659.50

PIMA547672 - Each of 1

₹ 47,659.50

In Stock

Quantity

1

Base Price: ₹ 47,659.50

GST (18%): ₹ 8,578.71

Total Price: ₹ 56,238.21

Antigen

CD298

Classification

Monoclonal

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P54709

Gene Symbols

ATP1B3

Immunogen

Clone (M016) was generated from a proprietary antigen related to the native human Na+/K+ ATPase beta3 subunit expressed in A431 epidermoid carcinoma cell line.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

M016

Conjugate

Unconjugated

Gene

ATP1B3

Gene Alias

AA409958; AI664000; Atp1b3; ATPase Na+/K+ transporting subunit beta 3; ATPase, Na+/K+ beta 3 polypeptide; ATPase, Na+/K+ transporting, beta 3 polypeptide; ATPase, Na+K+ transporting, beta polypeptide 3; ATPB-3; AW212096; CD298; CD298 antigen; Na K-ATPase beta-3 subunit; Na+/K+ -ATPase beta 3 subunit; NKAB3S; Sodium Potassium ATPase; Sodium/potassium-dependent ATPase subunit beta-3; sodium/potassium-transporting ATPase subunit beta-3

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

483

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG1

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Description

  • Clone M016 mouse monoclonal antibody detects a 40 kDa* protein on SDS-PAGE Native immunoblots of human A431, LNCaP, MeWo, MDA-MB-231, and MCF7 cells
  • This antibody does not detect denatured Na+/K+ ATPase beta3 subunit
  • In addition, mass spectrometry analysis of immunoprecipitates using NM0161 in human A431 cell lysates confirms that this antibody only detects Na+/K+ ATPase beta3 protein.The antibody works for western blot, immunoprecipitation, ELISA, and immunocytochemistry, as well as detects the beta3 subunit on live cells
  • The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases
  • Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane
  • These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle
  • This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta)
  • The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane
  • The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes
  • This gene encodes a beta 3 subunit
  • This gene encodes a beta 3 subunit
  • A pseudogene exists for this gene, and it is located on chromosome 2.