PIMA547700
Caspase 6 Monoclonal Antibody (M378), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547700-Each-of-1 | In Stock | ₹ 40,851.00 |
PIMA547700 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,851.00
GST (18%): ₹ 7,353.18
Total Price: ₹ 48,204.18
Antigen
Caspase 6
Classification
Monoclonal
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
P55212
Gene Symbols
Casp6
Immunogen
Clone (M378) was generated from a peptide containing amino acid residues in the C-terminal region of human Caspase-6.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Western Blot
Clone
M378
Conjugate
Unconjugated
Gene
Casp6
Gene Alias
apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
839
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG1
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Description
- The antibody detects a 34 kDa* protein corresponding to the molecular weight of Caspase-6 on SDS-PAGE immunoblots of human Jurkat, K562, and A431 cells
- Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
- Caspases have the ability to cleave after aspartic acid residues
- There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition)
- Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9
- Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.