Girdin Monoclonal Antibody (M012), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547719-Each-of-1 | In Stock | ₹ 46,769.50 |
PIMA547719 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,769.50
GST (18%): ₹ 8,418.51
Total Price: ₹ 55,188.01
Antigen
Girdin
Classification
Monoclonal
Concentration
∽0.125 mg/mL
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
Q3V6T2
Gene Symbols
CCDC88A
Immunogen
Clone (M012) was generated from a recombinant protein that included amino acid residues within the C-terminal region of human Girdin.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone
M012
Conjugate
Unconjugated
Gene
CCDC88A
Gene Alias
A430106J12Rik; AI848406; Akt phosphorylation enhancer; AKT-phosphorylation enhancer; Ape; C130096N06Rik; C330012F17Rik; Ccdc88a; coiled coil domain containing 88A; coiled-coil domain containing 88A; coiled-coil domain-containing protein 88A; D130005J21Rik; G alpha-interacting vesicle-associated protein; Galpha-interacting vesicle-associated protein; girders of actin filament; girders of actin filaments; girdin; GIV; Grdn; HkRP1; Hook-related protein 1; KIAA1212; RGD1306694
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
55704
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG1
Related Products
Description
- Clone M012 mouse monoclonal antibody detects a 250 kDa* protein on SDS-PAGE immunoblots of human A431 cells and human brain tissue
- The antibody also works for immmunoprecipitation, immunohistochemistry, and immunocytochemistry
- Girdin is a Galpha-interacting protein that can enhance the activation of the protein kinase Akt, remodel the actin cytoskeleton, and is thought to be involved in the regulation of cell migration and cancer metastasis
- It has recently been shown that Girdin interacts with Disrupted-in-Schizophrenia 1 (DISC1), a susceptibility gene for major psychiatric disorders
- DISC1 is thought to be involved in the migration, positioning and differentiation of dentate granule cells (DGCs) during development; depletion of Girdin or blocking the Girdin-DISC1 interaction results in defects in axonal sprouting in the CA3 region of the hippocampus and overextended migration of mispositioning of DGCs, suggesting the Girdin plays a role in postnatal neurogenesis in the dentate gyrus.