PIMA547800

IL-4 Chimeric Recombinant Rabbit Monoclonal Antibody (11B11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547800-Each-of-1 In Stock ₹ 46,769.50

PIMA547800 - Each of 1

₹ 46,769.50

In Stock

Quantity

1

Base Price: ₹ 46,769.50

GST (18%): ₹ 8,418.51

Total Price: ₹ 55,188.01

Antigen

IL-4 Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P07750

Gene Symbols

Il4

Immunogen

BSF-1/IL-4 purified from serum-free supernatants of cultured EL-4 cells (a C57BL/6 thymoma) induced with 4beta-phorbol 12beta-myristate 12alpha-acetate for 48h.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry

Clone

11B11

Conjugate

Unconjugated

Gene

Il4

Gene Alias

B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16189

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

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Description

  • Specificity: Binds to a core functional region of murine IL-4, which prevents this cytokine from interacting with its cognate receptor
  • Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor
  • IL-4 has been found to have the broadest range of actions
  • The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13
  • STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4
  • The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q
  • In particular, IL-4 is located in close proximity to IL13 on the chromosome
  • Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome
  • IL-4 delta 2 is a known splice variant of IL-4.