PIMA547810

CD4 Recombinant Rat Monoclonal Antibody (YNB46.1.8 (Campath-9H)), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547810-Each-of-1 In Stock ₹ 46,769.50

PIMA547810 - Each of 1

₹ 46,769.50

In Stock

Quantity

1

Base Price: ₹ 46,769.50

GST (18%): ₹ 8,418.51

Total Price: ₹ 55,188.01

Antigen

CD4

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P01730

Gene Symbols

CD4

Immunogen

Rat T-cell line (NB2) transfected with the human CD4.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

YNB46.1.8 (Campath-9H)

Conjugate

Unconjugated

Gene

CD4

Gene Alias

Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species

Rat

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

920

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • Specificity: Recognizes the 55kDa human CD4 cell surface antigen, expressed by helper T lymphocytes and by monocytes
  • The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV
  • CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells
  • At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues
  • CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck
  • It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system
  • Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].