PIMA547858
CD7 Chimeric Recombinant Rabbit Monoclonal Antibody (3A1E), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547858-Each-of-1 | In Stock | ₹ 46,769.50 |
PIMA547858 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,769.50
GST (18%): ₹ 8,418.51
Total Price: ₹ 55,188.01
Antigen
CD7 Chimeric
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Gene Accession No.
P09564
Gene Symbols
CD7
Immunogen
Proprietary sequence.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot
Clone
3A1E
Conjugate
Unconjugated
Gene
CD7
Gene Alias
Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
924
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Specificity: Recognises human CD7
- CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily
- CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects
- CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia
- Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells
- Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation
- CD7 associates directly with phosphoinositol 3'-kinase
- CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation
- Expression of CD7 is an important marker used in leukemia diagnostics.