PIMA547934

CD357 (AITR/GITR) Chimeric Recombinant Rabbit Monoclonal Antibody (YGITR 860.103.5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547934-Each-of-1 In Stock ₹ 46,769.50

PIMA547934 - Each of 1

₹ 46,769.50

In Stock

Quantity

1

Base Price: ₹ 46,769.50

GST (18%): ₹ 8,418.51

Total Price: ₹ 55,188.01

Antigen

CD357 (AITR/GITR) Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

O35714

Gene Symbols

Tnfrsf18

Immunogen

Mouse GITR.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry

Clone

YGITR 860.103.5

Conjugate

Unconjugated

Gene

Tnfrsf18

Gene Alias

Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21936

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

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Description

  • Specificity: This antibody binds to mouse GITR
  • Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene
  • It is mapped to 1p36.33
  • This gene encodes a member of the TNF-receptor superfamily
  • The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells
  • Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death
  • Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.