Nogo Receptor Recombinant Rabbit Monoclonal Antibody (M5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547935-Each-of-1 | In Stock | ₹ 46,769.50 |
PIMA547935 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,769.50
GST (18%): ₹ 8,418.51
Total Price: ₹ 55,188.01
Antigen
Nogo Receptor
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Gene Accession No.
Q99M75, Q99PI8, Q9BZR6
Gene Symbols
RTN4R
Immunogen
(His)6-tagged fragment of rat NgR1 (amino acids 278-473).
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunoprecipitation, Western Blot
Clone
M5
Conjugate
Unconjugated
Gene
RTN4R
Gene Alias
HGNC:1860; NgR; Ngr1; nogo 66 receptor; Nogo receptor; nogo receptor; Nogo-66 receptor; Nogo66 receptor; nogo-66 receptor; Nogo66 receptor-1; Nogor; OTTHUMP00000197866; reticulon 4 receptor; reticulon-4 receptor; Rtn4r; UNQ330/PRO526
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
113912, 65078, 65079
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG κ
Related Products
Description
- Specificity: The antibody binds to human and rat NgR1 with a Kd of 2.9 nM for both species (bivalent binding)
- NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG
- Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton
- NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS
- In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.