C5AR1 Chimeric Recombinant Rabbit Monoclonal Antibody (S5/1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA548288-Each-of-1 | In Stock | ₹ 46,769.50 |
PIMA548288 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,769.50
GST (18%): ₹ 8,418.51
Total Price: ₹ 55,188.01
Antigen
C5AR1 Chimeric
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Gene Accession No.
P21730, Q9TUE1
Gene Symbols
C5AR1
Immunogen
This antibody was raised by immunizing mice with a synthetic peptide corresponding to C5a-R, amino acids: 1-31 (N terminal).
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Bovine, Ferret, Human, Rabbit
Form
Liquid
Applications
ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunoprecipitation
Clone
S5/1
Conjugate
Unconjugated
Gene
C5AR1
Gene Alias
anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100352978, 101692871, 493645, 728
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG κ
Related Products
Description
- Specificity: S5/1 antibody recognizes the C5aR (CD88) protein, a 43 kDa receptor of C5a component of the complement cascade
- CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known
- C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract
- CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a
- Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production
- CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex
- Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.