PIMA549323

CD223 Recombinant Llama Monoclonal Antibody (1A6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA549323-Each-of-1 In Stock ₹ 39,071.00

PIMA549323 - Each of 1

₹ 39,071.00

In Stock

Quantity

1

Base Price: ₹ 39,071.00

GST (18%): ₹ 7,032.78

Total Price: ₹ 46,103.78

Antigen

CD223

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P18627, Q5BK54, Q61790

Gene Symbols

LAG3

Immunogen

A recombinant protein corresponding to amino acids 23-434 of human LAG3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

1A6

Conjugate

Unconjugated

Gene

LAG3

Gene Alias

Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Host Species

Llama

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16768, 297596, 3902

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

scFv

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Description

  • LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
  • LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
  • Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
  • CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
  • Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).