PIMA549578

CTLA-4 Monoclonal Antibody (KT56), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA549578-Each-of-1 In Stock ₹ 53,222.00

PIMA549578 - Each of 1

₹ 53,222.00

In Stock

Quantity

1

Base Price: ₹ 53,222.00

GST (18%): ₹ 9,579.96

Total Price: ₹ 62,801.96

Antigen

CTLA-4

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P16410

Gene Symbols

CTLA4

Immunogen

Recombinant Human CTLA4 (P00260PB)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Clone

KT56

Conjugate

Unconjugated

Gene

CTLA4

Gene Alias

ALPS5, CD, CD152, CD152 antigen, CD152 isoform, CD152 protein, CD152 protein precursor, celiac disease 3, CELIAC3, Ctla4, CTLA-4, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte associated protein 4, cytotoxic T-lymphocyte protein 4, cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM, cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, EGK_04712, GRD4, GSE, ICOS, IDDM12, insulin-dependent diabetes mellitus 12, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4, Ly-56, sCTLA4, soluble form, transmembrane form

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1493

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • This product was used in both Indirect and Sandwich ELISA
  • CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells
  • It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28
  • However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning
  • Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.