Placental Alkaline Phosphatase Monoclonal Antibody (5B1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMIA1802-Each-of-1 | In Stock | ₹ 71,467.00 |
PIMIA1802 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 71,467.00
GST (18%): ₹ 12,864.06
Total Price: ₹ 84,331.06
Antigen
Placental Alkaline Phosphatase
Classification
Monoclonal
Concentration
5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
P05187
Gene Symbols
ALPP
Immunogen
Purified human placenta ALP
Quantity
1 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunoprecipitation, Radioimmune Assays (RIA)
Clone
5B1
Conjugate
Unconjugated
Gene
ALPP
Gene Alias
Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; Alp1; ALPP; AP-TNAP; DOA1; FLJ11281; FLJ40094; FLJ61142; FLJ93059; Germ-cell alkaline phosphatase; glycerophosphatase; HOPS; MGC161443; MGC167935; nagao Isozyme; P PLAP; PALP; PLA2P; PLAA; placental alkaline phosphatase 1; placental heat-stable alkaline phosphatase; PLAP; PLAP1; PLAP-1; rCG23846-like; Regan isozyme; TNAP; TNSALP
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
250
Content And Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Form
Liquid
Related Products
Description
- MIA1802 targets Alkaline Phosphatase in ELISA, IP, and RIA applications and shows reactivity with Human samples
- The MIA1802 immunogen is purified human placenta ALP
- MIA1802 detects Alkaline Phosphatase which has a predicted molecular weight of approximately 59 kDa
- MIA1802 was formerly sold as a Seradyn product
- Placental Alkaline Phosphatase plays an important role in the regulation of specific inflammatory disease processes
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney for this form of alkaline phosphatase have been well characterized
- Placental Alkaline Phosphatase reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation
- Placental Alkaline Phosphatase is useful in the identification of testicular germ cell tumors
- Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA)
- A proposed function of Placental Alkaline Phosphatase is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development
- Placental Alkaline Phosphatase has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects
- The character of hypophosphatasia can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.