PIOST00047W
TRPV6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIOST00047W-Each-of-1 | In Stock | ₹ 42,898.00 |
PIOST00047W - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
TRPV6
Classification
Polyclonal
Gene
TRPV6
Gene Alias
ABP/ZF, CAT1, CATL, ECAC2, HSA277909, LP6728, ZFAB
Host Species
Sheep
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Gene Accession No.
Q9H1D0
Gene Symbols
TRPV6
Immunogen
A synthetic peptide from human TRPV6 conjugated to an immunogenic carrier protein
Regulatory Status
RUO
Gene ID (Entrez)
55503
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
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Description
- Reconstitute with 100 μL of distilled water
- Calcium-permeable channels, such as TRPV6, participate in neurotransmission, muscle contraction, and exocytosis by providing calcium as an intracellular second messenger
- Depending on the tissue, transcellular calcium transport may be regulated by vitamin D, parathyroid hormone (PTH), or calcitonin (CALCA)
- Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine
- The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification
- Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation
- In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner
- Heteromeric assembly with TRPV5 seems to modify channel properties
- TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating
- Interacts with TRPV5
- Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer
- The interaction with S100A10 is required for the trafficking to the plasma membrane
- Interacts with BSPRY
- Interacts with calmodulin.