GRB2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA110033-Each-of-1 | In Stock | ₹ 42,987.00 |
PIPA110033 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,987.00
GST (18%): ₹ 7,737.66
Total Price: ₹ 50,724.66
Antigen
GRB2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRB2
Gene Alias
AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2885
Content And Storage
4° C, do not freeze
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.
P62993
Gene Symbols
GRB2
Immunogen
Synthetic peptide corresponding to C-terminus of human Grb2 (amino acids 198-217).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The immunogen has 100% identity between man, cow, rat and mouse
- Western Blot: Reducing conditions
- GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain
- In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos
- The GRB 2-Sos complex then binds the EGF receptor
- These interactions play a critical role in the activation of the p21 ras signaling pathway.