PIPA112724
SGPP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA112724-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA112724 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
SGPP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SGPP2
Gene Alias
FLJ39004; RGD1565739; SGPP2; sphingosine 1-phosphate phosphohydrolase 2; sphingosine-1-phosphatase 2; Sphingosine-1-phosphate phosphatase 2; sphingosine-1-phosphate phosphotase 2; Spp2; SPPase2
Host Species
Rabbit
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with no preservative
Gene Accession No.
Q8IWX5
Gene Symbols
SGPP2
Immunogen
Synthetic peptide corresponding to sphingosine 1-phosphate phosphatase 2.
Regulatory Status
RUO
Gene ID (Entrez)
130367
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- By Western blot, PA1-12724 detects a ∽45 kDa protein representing S1P Phosphatase 2 from human brain lysate
- Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/Gprotein- coupled receptors of the endothelial differentiation gene family
- Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P
- SPPase2 is localized to the endoplasmic reticulum
- The enzymatic activity and localization of SPPase2 are similar to SPPase1
- The tissue expression of SPPase2 was different from that of SPPase1
- SPPase2 is an important member of the SPPase family whichplay a role in attenuating intracellular S1P signaling.