EDG6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA120778-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA120778 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
EDG6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
S1PR4
Gene Alias
Edg6; EDG-6; Endothelial differentiation G-protein coupled receptor 6; endothelial differentiation G-protein-coupled receptor 6; endothelial differentiation, G protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6; LPC1; Lysophospholipid receptor C1; S1P receptor 4; S1P receptor Edg-6; S1P(4) receptor; S1p4; S1PR4; SLP4; sphingosine 1-phosphate receptor 4; Sphingosine 1-phosphate receptor Edg-6; sphingosine-1-phosphate receptor 4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8698
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
O95977
Gene Symbols
S1PR4
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human EDG6
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description PA1-20778 detects S1P4 in Human samples
- EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids
- The ligand for EDG6 (S1P4) is sphingosine-1-phosphate
- There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis
- They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis
- EDG receptors are developmentally regulated and differ in tissue distribution
- They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases
- EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs
- Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor
- Thus, the new designation for the EDG6 (S1P4) receptor is the sphingosine 1-phosphate receptor-4 (S1P4).