P2X2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA124624-Each-of-1 | In Stock | ₹ 49,083.50 |
PIPA124624 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,083.50
GST (18%): ₹ 8,835.03
Total Price: ₹ 57,918.53
Antigen
P2X2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
P2RX2
Gene Alias
ATP receptor; DFNA41; MGC129601; P2RX2; P2X purinoceptor 2; P2X Receptor, subunit 2; P2X2; P2X2 purinoceptor; P2X2 receptor splice variant P2X2-1; P2X2 receptor splice variant P2X2-2; P2X2 receptor splice variant P2X2-3; P2X2a; Purinergic receptor; purinergic receptor P2X 2; purinergic receptor P2X, ligand gated ion channel, 2; purinergic receptor P2X, ligand-gated ion channel, 2; purinergic receptor P2X2
Host Species
Rabbit
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Guinea Pig, Human, Mouse, Non-human Primate, Porcine, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 0.05% sodium azide
Gene Accession No.
O70397, P49653, Q8K3P1, Q9UBL9
Gene Symbols
P2RX2
Immunogen
Synthetic peptide corresponding to residues D(460) S T S T D P K G L A Q L(472) of rat P2X2.
Regulatory Status
RUO
Gene ID (Entrez)
100135591, 100736581, 114115, 22953, 231602
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Description PA1-24624 is expected to cross react with mouse (100% conserved) and guinea pig (100% conserved) due to sequence homology
- P2rx2 are members of the ligand-gated ion channel family that open in response to extracellular ATP
- Each receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains
- P2rx2 functions as a ligand-gated ion channel and binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle
- Six transcript variants encoding six distinct isoforms have been identified for P2rx2
- P2rx2 is involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis
- In the inner ear, P2rx2 regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling
- P2rx2 also mediates synaptic transmission between neurons and from neurons to smooth muscle
- Diseases associated with P2RX2 include Deafness, Autosomal Dominant 41 and Dfna41 Nonsyndromic Hearing Loss And Deafness.