PIPA125162
Zyxin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA125162-Each-of-1 | In Stock | ₹ 52,599.00 |
PIPA125162 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,599.00
GST (18%): ₹ 9,467.82
Total Price: ₹ 62,066.82
Antigen
Zyxin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ZYX
Gene Alias
9530098H06Rik; ESP-2; HED-2; LOW QUALITY PROTEIN: zyxin; R75157; ZYX; Zyxin; zyxin-2
Host Species
Rabbit
Purification Method
IgG fraction
Regulatory Status
RUO
Gene ID (Entrez)
114636, 22793, 7791
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
12.7 mg/mL
Formulation
0.01M PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
Q15942, Q62523
Gene Symbols
ZYX
Immunogen
Synthetic peptide, conjugated to KLH at an N-terminal added cysteine, corresponding to residues 134-150 of human Zyxin.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HeLa, Rat1
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Zyxin is involved in focal adhesions, which are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble
- Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton
- Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half
- The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding
- Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles
- Alternative splicing results in multiple transcript variants that encode the same isoform.