PIPA125309

MMP25 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA125309-Each-of-1 In Stock ₹ 46,502.50

PIPA125309 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MMP25

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mmp25

Gene Alias

F730048C11Rik; Leukolysin; matrix metallo protease; matrix metallopeptidase 25; matrix metallopeptidase-like 1; matrix metalloproteinase 20; matrix metalloproteinase 25; matrix metalloproteinase-25; matrix metalloproteinase-like 1; membrane-type 6 matrix metalloproteinase; membrane-type matrix metalloproteinase 6; Membrane-type-6 matrix metalloproteinase; MMP; MMP 25; MMP20; MMP20A; Mmp25; MMP-25; MMPL1; MMPs; MT MMP 6; MT6 MMP; MT6MMP; MT6-MMP; MT-MMP 6; MTMMP6; MT-MMP6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

64386

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

0.01M PBS with 50% glycerol and 0.05% sodium azide

Gene Accession No.

Q9NPA2

Gene Symbols

Mmp25

Immunogen

Synthetic peptide corresponding to the propeptide domain of human MMP-28.

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis
  • Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases
  • However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor
  • In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites
  • The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2
  • The gene has previously been referred to as MMP20 but has been renamed MMP25.