MEK3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA128434-Each-of-1 | In Stock | ₹ 51,397.50 |
PIPA128434 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,397.50
GST (18%): ₹ 9,251.55
Total Price: ₹ 60,649.05
Antigen
MEK3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAP2K3
Gene Alias
AW212142; dual specificity mitogen-activated protein kinase kinase 3; EC 2.7.12.2; MAP kinase kinase 3; Map2k3; MAPK/ERK kinase 3; MAPKK 3; MAPKK3; MEK 3; Mek3; mitogen activated protein kinase kinase 3; mitogen-activated protein kinase kinase 3; Mkk3; mMKK3b; Prkmk3; protein kinase, mitogen-activated, kinase 3; SAPK kinase 2; SAPKK2; SAPKK-2; SKK2; Stress-activated protein kinase kinase 2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
26397, 5606
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide; pH 7.2
Gene Accession No.
O09110, P46734
Gene Symbols
MAP2K3
Immunogen
Recombinant protein - full length human MKK3
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description PA1-28434 detects MKK3 from human samples
- MAP2K3 (MEK3) is a dual-specificity protein kinase which acts in cellular signal transduction pathways, and is necessary for the expression of glucose transporter
- It phosphorylates and thus activates MAPK14/p38-MAPK
- This kinase can be activated by insulin, and is necessary for the expression of glucose transporter
- Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells
- The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis
- Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for MEK3.