PIPA129165

CD263 (TRAIL-R3) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA129165-Each-of-1 In Stock ₹ 48,905.50

PIPA129165 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

CD263 (TRAIL-R3)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFRSF10C

Gene Alias

Antagonist decoy receptor for TRAIL/Apo-2L; CD263; cytotoxic TRAIL receptor-3; DCR1; DCR1-TNFR; Decoy receptor 1; decoy TRAIL receptor without death domain; LIT; lymphocyte inhibitor of TRAIL; MGC149501; MGC149502; TNF receptor superfamily member 10c; TNF-related apoptosis-inducing ligand receptor 3; TNFRSF10C; TRAIL receptor 3; TRAIL receptor without an intracellular domain; TRAILR3; TRAIL-R3; TRID; Tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; UNQ321/PRO366

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

8794

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

10mM PBS with 0.2% BSA and 0.1% sodium azide

Gene Accession No.

O14798

Gene Symbols

TNFRSF10C

Immunogen

Synthetic peptide corresponding to the N-terminal extracellular domain of human DcR1 precursor protein

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: Placenta TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily
  • This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain
  • This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis
  • This gene was found to be a p53-regulated DNA damage-inducible gene
  • The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.