PGP9.5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA146205-Each-of-1 | In Stock | ₹ 52,421.00 |
PIPA146205 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,421.00
GST (18%): ₹ 9,435.78
Total Price: ₹ 61,856.78
Antigen
PGP9.5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Uchl1
Gene Alias
AW822034; C88048; epididymis luminal protein 117; epididymis secretory protein Li 53; gad; gracile axonal dystrophy; HEL-117; HEL-S-53; MGC133697 protein; NDGOA; neuron cytoplasmic protein 9.5; OTTHUMP00000218137; OTTHUMP00000218139; OTTHUMP00000218140; OTTHUMP00000218141; PARK5; PGP 9.5; PGP9.5; PGP95; protein gene product 9.5; R75593; ubiquitin carboxyl-terminal esterase; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin carboxyl-terminal hydrolase L1; ubiquitin carboxy-terminal hydrolase L1; ubiquitin C-terminal hydrolase; ubiquitin C-terminal hydrolase 1; ubiquitin C-terminal hydrolase L1; ubiquitin thioesterase L1; ubiquitin thiolesterase; ubiquitin thiolesterase L1; UCHL; UCHL1; UCH-L1; UCHL-1
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 5mM sodium azide
Gene Accession No.
P09936, P23356, Q00981, Q6SEG5, Q9GM50, Q9R0P9
Gene Symbols
Uchl1
Immunogen
Recombinant full length human UCHL1 purified from E. coli.
Regulatory Status
RUO
Gene ID (Entrez)
100033838, 22223, 29545, 396637, 514394, 7345, 770302
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Suggested positive control: antigen standard for UCHL1 (transient overexpression lysate), SH-SY5Y neuroblastoma lysate and rat spinal cord and peripheral nerve homogenate
- PGP9.5 (Protein gene product 9.5, UCH-L1, PARK5) is a neuron specific protein, structurally and immunologically distinct from neuron specific enolase
- PGP9.5 has a molecular weight of 27 kDa and was first identified by high resolution two dimensional PAGE
- PGP9.5 is a member of ubiquitin carboxyl-terminal hydrolase family 1 (peptidase family C12) with a ubiquitin carboxyl-terminal hydrolase domain
- PGP9.5 is well known for having ubiquitin hydrolase and ligase activities that hydrolyzes small C-terminal adducts of ubiquitin to generate ubiquitin monomers
- PGP9.5 is present in neurons and nerve fibers at all levels of the central and peripheral nervous system, in neuroendocrine cells, in segments of the renal tubules, in spermatogonia and Leydig cells of the testis, in ova and in some cells of both the pregnant and non-pregnant corpus luteum
- Over expression of PGP9.5 leads to non-small cell lung cancer while decreased expression leads to Huntington disease and Alzheimer disease
- Since PGP9.5 is present in cellular inclusions, it can be a useful as a neuronal marker and in the studies of neurodegenerative disorders such as with Parkinson disease.