PIPA14963
HIV1 nef Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA14963-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA14963 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
HIV1 nef
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
HIV-1 Nef
Immunogen
Purified full-size recombinant Nef of HIV1 group M, subtype B expressed in E. coli.
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG
Applications
Dot Blot, ELISA, Immunoprecipitation, Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 0.09% sodium azide
Host Species
Guinea Pig
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- PA1-4963 detects the HIV-1 Nef protein in HIV samples
- PA1-4963 has been successfully used in Western blot and ELISA procedures
- By Western blot this antibody detects a ∽27 kDa protein, corresponding to HIV-1 Nef in HIV samples
- PA1-4963 immunogen corresponds to the recombinant protein which was over-expressed in E
- coli with a plasmid carrying the Nef coding region of the HIV-1 virus
- Recombinant HIV-1 Nef protein (Cat
- # RP-4922 or RP-4923) can be purchased for control experiments in Western blot assays
- HIV-1 Nef is one of the accessory proteins synthesized in the early stage of AIDS virus reproduction and is abundantly found in infected cells
- The name derives from its negative factor thought at the beginning but presently it is remarked as the protein which bears a most distinctive biological characteristic of AIDS virus
- The protein interacts directly with the signal transduction protein of the host T cell and works effectively on AIDS infection or on long term survival of the infected cells or induces apoptosis of non-infected cells
- It is also involved in the endocytosis and degradation of receptor protein of the cell surface such as CD 4 and MH4, important for AIDS virus infection.