DIS3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100140-Each-of-1 | In Stock | ₹ 45,345.50 |
PIPA5100140 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,345.50
GST (18%): ₹ 8,162.19
Total Price: ₹ 53,507.69
Antigen
DIS3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DIS3
Gene Alias
2810028N01Rik; bA555G22.1; DIS3; DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; DIS3 mitotic control homolog; DIS3 mitotic control homolog (S. cerevisiae); dis3p; EXOSC11; exosome complex exonuclease RRP44; exosome component 11; KIAA1008; mitotic control protein dis3 homolog; protein DIS3 homolog; RGD1304646; Ribosomal RNA-processing protein 44; RP11-342J4.3; RRP44
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22894, 306103, 72662
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q9CSH3, Q9Y2L1
Gene Symbols
DIS3
Immunogen
A synthesized peptide derived from human DIS3(Accession Q9Y2L1), corresponding to amino acid residues L736-I786.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total DIS3
- The exosome is involved in a multitude of cellular RNA processing and degradation events
- DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species
- DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain
- It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, μgtimately, for proper mitotic progression
- Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.