OPHN1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100164-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5100164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
OPHN1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
OPHN1
Gene Alias
ARHGAP41; C130037N19Rik; mental retardation, X-linked 60; MRX60; oligophrenin 1; oligophrenin-1; oligophrenin-1, Rho-GTPase activating protein; Ophn1; Opn1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
312108, 4983, 94190
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O60890, P0CAX5, Q99J31
Gene Symbols
OPHN1
Immunogen
A synthesized peptide derived from human OPHN1(Accession O60890), corresponding to amino acid residues L222-L272.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total Oligophrenin 1
- Stimulates GTP hydrolysis of members of the Rho family
- Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function
- Critical for the stabilization of AMPA receptors at postsynaptic sites
- Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals
- Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.