PIPA5100198

RASSF10 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100198-Each-of-1 In Stock ₹ 46,502.50

PIPA5100198 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

RASSF10

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RASSF10

Gene Alias

4632411J06Rik; Ras association (RalGDS/AF-6) domain family (N-terminal) member 10; Ras association domain family member 10; ras association domain-containing protein 10; Rassf10

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

644943

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

A6NK89

Gene Symbols

RASSF10

Immunogen

A synthesized peptide derived from human RASSF10(Accession A6NK89), corresponding to amino acid residues M466-V507.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total RASSF10
  • RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer
  • These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains
  • While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas
  • In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.