RIC8A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100318-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5100318 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
RIC8A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RIC8A
Gene Alias
AI114950; heterotrimeric G protein guanine nucleotide exchange factor Ric-8A; MGC104517; MGC131931; MGC148073; MGC148074; Protein Ric-8A; resistance to inhibitors of cholinesterase 8 homolog; resistance to inhibitors of cholinesterase 8 homolog (C. elegans); resistance to inhibitors of cholinesterase 8 homolog A; resistance to inhibitors of cholinesterase 8A; Ric8; RIC-8; RIC8 guanine nucleotide exchange factor A; RIC8 protein; Ric8a; Ric-8A; synembryn; synembryn-A
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
101489, 293614, 60626
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q3TIR3, Q80ZG1, Q9NPQ8
Gene Symbols
RIC8A
Immunogen
A synthesized peptide derived from human RIC8A(Accession Q9NPQ8), corresponding to amino acid residues K476-P526.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total RIC8A
- Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins
- Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP
- Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex
- Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.